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babblingmusic...movie...series... July 24 Breaking newseven though it's still a challenge and certainly a very controversial subject to generate human beings from any type stem cells, apparently it works with mice!
two groups in China just reported making mice from induced pluripotent stem cells (iPS): one from CAS (State Key Laboratory of Reproductive Biology) published a letter in Nature, and the other from Chinese Academy of Medical Sciences and Peking Union Medical College made it to the also prestigious Cell Stem Cell.
here's the Nature news:
Stem cells: Live mice from fibroblast
Stem cells induced from somatic cells can be as pluriopotent as stem cells extracted from embryos, research published online by Nature has demonstrated this week. A team from China created induced pluripotent stem (iPS) cell lines from mouse fibroblasts, before showing that these cells could go on to generate fertile live mouse pups, the first born of which they named Tiny.*
Qi Zhou, Fanyi Zeng and colleagues report the generation of 37 iPS cell lines, three of which produced 27 live offspring by tetraploid complementation. One of these, a 7-week-old male, went on to impregnate a female and produce young of its own. *In Chinese "小小“ written as "Xiao Xiao", which sounds like "Shau Shau".
full article in Nature:
"iPS cells produce viable mice through tetraploid complementation"
report in Cell Stem Cell:
"iPS cells can support full-term development of tetraploid Blastocyst-complemented embryos"
December 30 jp tv好久没有(不用快进)看日剧，但是硬盘告急，美剧的质量/空间ratio比较高，于是决定从那几十部存了又没看的日剧下手.............周末两个晚上竟然搞定两部...........
bloody monday 才播完的，当时因为被海报上三浦同学的侧面震撼到于是打算看看要不要追，主题是hacker+virus+terrorist+patriot+nuclear weapon(?)........前两集看的我为里面hacking的那一显示屏code欲罢不能想说真是很久没有让我能一集一集追的日剧了结果第三集就没看下去.......不过等完结了一口气看完也还是不错的，虽然播放期间也有剧透无数不过悬念还是有一点的，比较起来的话日本在高科技反恐这个方面和美国的同类剧还是没办法比的，还有就是演员的话........大概普遍日系演员演戏比较用力......更不要说年轻的一代了......倒是佐藤sato君没有我想象中那么糟糕，本来以为特摄拍多了也会演技比较夸张的，这部里面倒还好——当然一方面也是因为他没有什么戏份....... 男一号haruma君的演绎.......也还好吧........毕竟人家才18岁、要求不能太高.....中间有一场哭戏是在看到同学染病即将身亡却仍在鼓励自己的时候，本来是很感动的场面结果我被他突然用手捂住嘴哭泣的乙女状呕到了.....想说你看旁边的女生都没有像你这样啊.........不过临近ending时那个几乎放弃一切静静流下泪的场景还是很加分的...... 回想起来原来整部剧haruma君给印象最深的就是那个海报上的侧面了........ 成宫宽贵的J还不错，那种很嚣张的leader姿态由他演来没想到还不错，然后扮纯良数学家的时候也还比较可信........不过为什么会喜欢喝melon soda啊？！那种颜色很可疑的东西怎么能放进嘴里啊........... 意料之外女一号(?)虽然开始没有很喜欢却是越看越舒服，喜欢她那种慢悠悠一切尽在掌握的态度，还有声音也很性感....... 整部剧最后也算有点意料之外，就在大家都以为东京是要毁在virus手上却没有想到最终boss是nuclear weapon.......其实也没差，反正都是要被毁掉的......orz.... ....虽然期间吐糟无数、纠结bug无数....总的来说还是可以一看的剧........音乐不错，听井筒昭雄做的tv音乐也不是第一次了。主题曲的乐队flumpool也很棒，走britrock风让我想到一点点TBG，unreal整张专辑都很赞 貧乏男子
选中这部看是因为剧情不是我喜欢的型可以随便看看就删掉解救硬盘........当初下这部也只是看到小栗主演而且号称"小栗旬打破形象上演sports装show"引得我好奇........当然另外就是正好TVBT做了这部...... 于是开始看，看完第一话前5分钟，证实：1果然不是我喜欢的类型；2小栗果然tension高到那5分钟内竟然来回有跑到一万米。然后立刻转去最后一话的最后5分钟，想说看完这5分钟就可以删了～不料，在最后5分钟的场景看到了很眼熟的人(shun君除外)....于是暂停又倒回几秒反复看了，终于确认——这个不是刚刚在BloodyMonday里的haruma君吗？！我也没有很迷他为什么接连两部剧里都有他啊........于是wiki了一下cast，果然有三浦春马的名字而且还是主役——本来还想只看有他出现的话数就好了不料这个家伙从第一话第6分钟开始一直悠悠演到最后一话倒数第4分钟........ 一边快进一边看，有haruma出场就停下来，不过这个家伙的场景也都是和小栗对手戏，看了一会儿渐渐想起来当时这部剧在播出的时候我其实看过某一话的图透，那个作者yy这两位我当时也没什么感觉只觉得小栗以外的那只的确是清秀可爱配小栗稍稍可惜了点.....原来那个时候就见过haruma了....再看一会儿，连我一向不yy真人couple的都忍不住吐糟——拜托两位不要一对戏就深情对视眼泪汪汪了好不好>_< 小栗那样表情有点惨不忍睹、haruma那样还是比较有杀伤力的啊～不过那个没有事干就冲去某人公寓问候某人、送给/接受某人东西、以某人为日记主题、竟然还因为心疼某人打工晚归辛苦而主动替人家做饭的人是谁啊？！haruma你的角色好歹在剧中是有暗恋女生的、你干嘛在邻居小栗君面前那么人妻样啊！！！这个和BM里面也差太多了吧........还是说其实这种柔顺乙女态其实才是本性？！果然在BM里面让你拯救东京是太难为你了........ 看完，感叹：
小栗你果然穿了很多套颜色搭配诡异的运动服，好在身材高挑所以视觉效果还有得挽救； 第一次看山田优的戏，意料外的喜感很不错....这部剧里很多演员都喜感不错的； 整部戏以我的胃口来看tension过于高了，小栗体力堪比樱木花道了，完全以跑代走，倒是不浪费那么多运动装。不过既然是热血主题当然就少不了感动戏，有一些细节还是蛮感人的，父子情和母子情那里，还有小栗真的是很辛苦赚钱还债的场景 最后....haruma君.....虽然不愿意承认...但....比起BM...你果然还是适合回归本性的小媳妇状啊....... October 15 H. Y.i saw howard young today. the millionaire who suffers from pancreatic cancer, the man who told us two years ago that he would personally sponsor us if we didn't get our NIH funding.
he came here today. bossman wanted to introduce me to him, but i ducked.....if it's just about talking, bossman is better at bsing than me.
he was only outside our lab for half hour maybe. he and three PIs were just talking outside our computer room. his voice was a little weak, probably because of the chemo session he had yesterday.
truth is, i would've felt guilty facing him, because i know i'm not, and we're not doing our best in this project. the way he looked today just reminded of...everything i've been trying to get over with for the past two months.
there are hundreds of labs out there doing cancer biomarker research for decades, and NIH funds probablly more than half of them, yet still today we are using CA19-9, PSA, BRAC etc. for diagnosis, which creat false positive or false negative results all over the place.
we brag about medical development and scientific technology advancing all the time, and we can say that we're able to save millions of people who would've not even standed a chance to live 10 years ago. the reality is, there's always challenge in front of us, and we can not save everybody.
i have to realize that and keep that in mind, otherwise the frunstration alone would kill me.
i'm aware of that i'm not, and our lab is not obligated to him. after all, it's not his money we're wasting here......it's just his life...... October 07 .............i guess no matter how much you love your job, there's always some time that you just want to get away from it and not thinking about it.....
it's nothing contradictive, it's just....when you keep doing one thing for a long time, it becomes regular, becomes routine, and you need a change, a refresment, so that after which you can go back to work and start feeling the passion again.....
i haven't gotten to that place, well....not yet. but i have no doubt that someone, who's been in the same line of work for 20 years, would want to go to someplace once a while where he doesn't need to be reminded of his job at all, even though he excels in his field, even though he's still passionate about it after 20 years.
.....from time to time, i do wish that fariy tales never end and we all live in a perfect world........
September 28 house"Cancer stem cells are real. They explain everything. They're like embryonic stem cells. ......"
quote from "House M. D." season 5 episode 2, 00:34:34 to 00:34:40
thank you!!
how can you not love this show......
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